|
KMID : 0358420070500010135
|
|
Korean Journal of Obstetrics and Gynecology
2007 Volume.50 No. 1 p.135 ~ p.141
|
|
|
Clinical value of serum vascular endothelial growth factor (VEGF) in ovarian diseases
|
|
Yoon Joo-Hee
Kim Dae-Hoon
Lew Young-Ok
|
|
|
Abstract
|
|
|
Objective: The aim of this study was to evaluate the concentration of serum VEGF and its relationship with the clinical parameters and the tumor markers in ovarian diseases.
Methods: We measured the serum VEGF concentrations by ELISA in 76 patients with benign ovarian disease, as well as 9 normal volunteers, 4 patients with ovarian borderline malignancy and 53 patients with ovarian cancer.
Results: There is a significant statistical difference between the serum VEGF levels in patients with benign ovarian disease (157.7±197.8 pg/ml) and ovarian cancer (344.7±372.2 pg/ml) (p<0.005).
Conclusion: Serum VEGF may help in the differential diagnosis between benign and malignant ovarian disease. We suggest that serum VEGF may be useful as a diagnostic tool in ovarian disease.
|
|
|
KEYWORD
|
|
|
Ovarian disease, VEGF
|
|
|
FullTexts / Linksout information
|
|
 
|
|
|
Listed journal information
|
|
  
|